Updates

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  jessica Young wrote a new blog entry:

  BOC Sciences Proudly Declares High PseudoUridine Productivity

  BOC Sciences, well known as the largest supplier of pseudoUridine in the world, announces that its yearly output currently surpasses 500 kg, indicating reliable efficiency and high productivity.
   
  Along with the explosion of the COVID-19 ...

  • Mar 31
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  jessica Young wrote a new blog entry:

  Protein-Based Fluorescent Nanoparticles Available Now

  Fluorescent nanoparticles are those widely used for purposes of fluorescent imaging, mainly of cells and tissues. A strong fluorophore or fluorescent nanoparticles are internalized into cells so that they can be imaged. The only purpose of such fluorophor...

  • Mar 31
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  jessica Young wrote a new blog entry:

  What is the severity of the Omicron mutation?

  Recently, many scientists around the world summarized what they have learned about Omicron (an emerging variant of SARS-CoV-2) so far, as reported in Nature.
   
  Researchers from all over the world are now studying the Omicron strain to learn more ab...

  • Mar 31
• 
  jessica Young wrote a new blog entry:

  Another PROTAC entered clinical study

  December 24, 2021—Accutar Biotechnology, a biotechnology company focused on AI drug development, announced that the FDA has approved its IND for AC0176 for the treatment of patients with metastatic decompensated refractory prostate cancer (mCRPC).
  ...

  • Mar 30
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  jessica Young wrote a new blog entry:

  Powering Pharma Future by Innovative Drug Delivery Solutions

  The history of drug administering can date back to the ancient Egyptian era, when sometimes clay pellets were used for drug delivery. Fast forward to the 1960s, when controlled drug delivery and time release systems were introduced, the technolo...

  • Mar 25
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  jessica Young wrote a new blog entry:

  Matched Antibody Pairs and Their Applications

  An antigen molecule could have multiple antigenic determinants, or known as epitopes. An antibody produced by the immune system can only bind to a specific epitope, while an antigen molecule could bind to different antibodies targeting different epitopes ...

  • Mar 10
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  jessica Young wrote a new blog entry:

  How to achieve target delivery of mRNA drugs to organs, cells,

  Cell Targeted Delivery
  In addition to organ-specific delivery, the researchers sought to target specific cell subpopulations in the liver by engineering ionizable lipid nanoparticles for selective delivery to hepatocytes and hepatic sinusoidal endothelia...

  • Mar 1
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  jessica Young wrote a new blog entry:

  Oncolytic Virus Engineering: The Future Key for Cancer Treatmen

  Oncolytic virus (OV) is a type of virus that can selectively infect and kill cancer cells. When infected cancer cells are destroyed by oncolysis, OVs continue to release new infectious virus particles to help destroy the remaining tumors without harm...

  • Mar 1
• 
  jessica Young wrote a new blog entry:

  Creative Proteomics Announces the Launch of Its New Metabolomic

  Creative Proteomics is an integrated company that provides proteomics, metabolomics, glycomics, and bioinformatics analysis services to researchers in the pharmaceutical, biotechnology, agriculture and nutrition industries, as well as academic and governm...

  • Mar 1
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  jessica Young wrote a new blog entry:

  Four Methods Helping the Study of Mitochondrial Gene Expression

  Harboring some circular and small genomes in human cells, mitochondria are recognizable for providing the cell with energy in the form of adenosine triphosphate (ATP) via OxPhos. However, with mitochondrial studies advancing, their significance was u...

  • Feb 25
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  jessica Young wrote a new blog entry:

  CD Genomics: Targeted Proteomics Analysis Service Now Available

  Bioinformatics-analysis Platform belongs to CD Genomics, which provides reliable next-generation and third-generation high-throughput sequencing data analysis, comprehensive technology services, database construction, and other related data analysis busin...

  • Feb 25
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  jessica Young wrote a new blog entry:

  Fermentation process of vancomycin (II)

  Temperature and pH
  
  The growth and reproduction of bacteria and the synthesis of products are all based on the catalysis of enzymes, and the catalysis of enzymes is related to temperature and pH. Based on kinetic factors, how to control orderly become...

  • Feb 25
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  jessica Young wrote a new blog entry:

  What Are Dextrans?

  Dextran is a polysaccharide comprised of d-glucopyranose (d-glucose) repeating units linked through glycosidic linkages. It is biocompatible, biodegradable, and presents antithrombotic and anti-inflammatory properties. Dextran functional hydroxy...

  • Feb 21
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  jessica Young wrote a new blog entry:

  Creative BioMart Established a Novel Sub-brand Creative BioMart

  Creative BioMart, an internationally recognized leading supplier of recombinant proteins, recently established a novel sub-brand “Creative BioMart Recombinant Allergen” that focuses on allergen-related study.
   
  Allergy is a common hyper...

  • Feb 6
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  jessica Young wrote a new blog entry:

  Novel Protein Degradation Technologies: LYTACs and AbTACs

  TPD (targeted protein degradation)
  
  Proteins are the bearers of life activities, and their structure determines their function. Alterations in protein conformation frequently result in disease. The use of small molecules to selectively modulate protei...

  • Jan 29
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  jessica Young wrote a new blog entry:

  Breakthrough! Scientists use rhesus monkey embryonic stem cells

  According to recent research, in the 1970s, the average male had 99 million sperm per milliliter of sperm, but by 2011, that number had plummeted to 47 million, a 53% decrease. According to Shanna Swan, an environmental medicine and public health pro...

  • Jan 25
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  jessica Young wrote a new blog entry:

  Liposomes Usher in a New Era for Drug Delivery Research

  Recently, it is reported that some stunning breakthroughs have been made in gene-editing techniques to treat diversified diseases. Clustered regularly interspaced short palindromic repeat (CRISPR) is such a gene-editing achievement, which has at...

  • Jan 19
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  jessica Young wrote a new blog entry:

  Nanopore direct sequencing of proteins with up to 100% accuracy

  Proteins are the primary constituents of living organisms and the primary carriers of life activities. Proteins with biological functions often have a certain spatial structure that is defined at various levels, the most important of which is th...

  • Jan 17
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  jessica Young wrote a new blog entry:

  Bacterial Polysaccharides and Their Research Innovations

  Bacteria are covered by polysaccharides at the outer surface in the form of capsules, glycoproteins, or glycolipids. Such a bacterial sugar coat constitutes the principal antigens in most pathogenic bacteria and plays an important...

  • Jan 17
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  jessica Young wrote a new blog entry:

  The Wide Application of Escherichia coli Fermentation in Microb

  The microbial fermentation process has been manipulated by humans and is widely used in the production of various foods and other commercial products, including pharmaceuticals. Microbial fermentation can also be used to identify microorganisms for d...

  • Jan 14
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  jessica Young wrote a new blog entry:

  Comprehensive protein interaction network helps discover candid

  Treatment options for COVID-19 remain limited. Researchers at the University of Helsinki and the University of Eastern Finland first searched for appropriate drug targets and reusable drugs and finally discovered six candidates with antiviral effects agai...

  • Jan 7
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  jessica Young wrote a new blog entry:

  Physicists have found new quantum effects in bilayer graphene

  Theorists at the University of Texas at Dallas and colleagues in Germany have for the first time observed a rare phenomenon in a very simple material, called the quantum anomalous Hall effect. Previous experiments have only found it in complex or subtle s...

  • Jan 5
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  jessica Young wrote a new blog entry:

  CD ComputaBio Announces 3D-QSAR Service for Drug Design and Scr

  CD ComputaBio, a reliable computational biology service provider located in New York, is always hammering at research and trials in order to provide customers with access to the latest software, technologies, and expertise at a competitive price and fast ...

  • Jan 4
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  jessica Young wrote a new blog entry:

  APIs production through microbial fermentation

  There are many microorganisms in the world, and these microorganisms play a very important role in human life. At present, the most extensive application field of microorganisms is pharmaceuticals. With the help of the microbial fermentation, many dr...

  • December 28, 2021
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  jessica Young wrote a new blog entry:

  What Are Chelating Agents?

  Chelating agents are organic compounds capable of linking together metal ions to form complex ring-like structures called chelates. They are also known as chelants, chelators, or sequestering agents.
  
  What Are Natural Chelating Agents?
  
  Citric, m...

  • December 27, 2021
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  jessica Young wrote a new blog entry:

  What is Endotoxin shock?

  When a large number of gram-negative pathogens in the lesion or bloodstream die, and a large amount of endotoxin released into the blood, endotoxemia can occur. A large amount of endotoxin acts on the body's macrophages, neutrophils, endothelial cell...

  • December 24, 2021
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  jessica Young wrote a new blog entry:

  Evidence Indicates mRNA COVID-19 Vaccine Protection for Pregnan

  It's reported that over 125,000 laboratory-confirmed COVID-19 cases are pregnant women, including thousands of hospitalized cases and 161 deaths by the end of September 2021. Though such an appalling number of SARS-CoV-2 infections happened to pregnant wo...

  • December 22, 2021
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  jessica Young wrote a new blog entry:

  New Nature study confirms that mRNA vaccines are effective agai

  Since the emergence of the Delta variant of the SARS-CoV-2 in many parts of the world, the number of so-called "breakthrough infections"—SARS-CoV-2 infection despite vaccination—has increased. Although the overall number is small, it raises qu...

  • December 22, 2021
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  jessica Young wrote a new blog entry:

  Glycosylation modification of therapeutic antibodies

  The structural and functional heterogeneity of therapeutic antibodies (IgG type) is achieved by post-translational modifications (PTM), among which the glycosylation of antibody Fc is the most heterogeneous one that can affect the stability of the mo...

  • December 20, 2021
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  jessica Young wrote a new blog entry:

  Latest Study: Coronavirus Kills Brain Cells

  As COVID-19 continues to wreak havoc in countries around the world, the sequelae of the coronavirus infection have caught the attention of scientists. The so-called COVID-19 sequelae are a series of new, recurrent or ongoing health problems that can occur...

  • December 16, 2021
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  jessica Young wrote a new blog entry:

  SARS-CoV-2 Glycosylation Profiling Service Now Available at CD

  CD BioGlyco, a biotechnology company that offers a full range of glycobiology-related products, analysis, custom synthesis, and design to help advance glycobiology research, now provides customers with comprehensive and accurate viral glycomics informatio...

  • December 15, 2021
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  jessica Young wrote a new blog entry:

  Acroscell Offers Cardiac Ion Channel Screen Panels to Detect an

  Acroscell, the mature division of Creative Bioarray, is dedicated to developing top-quality products and cutting-edge technologies for the academia, pharmaceutical, and biotechnology industries. As a service company with strong strength in the field of el...

  • December 13, 2021
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  jessica Young wrote a new blog entry:

  What is Mitochondria and its research history

  Mitochondria are organelles that are present in most cells and are covered by two layers of membranes. They are the energy-producing structure in cells and the main place for cells to carry out aerobic respiration. They are called "power houses". Its diam...

  • December 6, 2021
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  jessica Young wrote a new blog entry:

  Introduction to Classification and Application of Cellulase

  The optimum pH of cellulase is generally 4.5 to 6.5, which acts on cellulose and products derived from cellulose. Microbial cellulase is of great significance in converting insoluble cellulose into glucose and destroying cell walls in fruit and vegetable ...

  • December 5, 2021
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  jessica Young wrote a new blog entry:

  Brief introduction about Sirna

  Small interfering RNA (siRNA) is sometimes called short interfering RNA (short interfering RNA) or silencing RNA. It is a double-stranded RNA with a length of 20 to 25 nucleotides. There are many in biology Different uses. It is currently known that siRNA...

  • December 2, 2021
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  jessica Young wrote a new blog entry:

  Nature: Structure-based classification of tauopathies

  Abnormal accumulation of misfolded tau in filaments is characteristic of many neurodegenerative diseases—precisely for this reason, these neurodegenerative diseases are collectively referred to as tauopathy. The Michel Goedert team and the Sjors Sch...

  • November 29, 2021
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  jessica Young wrote a new blog entry:

  Another zoonotic virus! One case of death from Nipah virus infe

  According to the Associated Press, India's southern state of Kerala is rapidly ramping up efforts to halt an outbreak of the deadly Nipah virus, despite the fact that the state is currently battling SARS-CoV-2 that poses a greater threat.
   
  Kerala ...

  • November 29, 2021
• 
  jessica Young wrote a new blog entry:

  Production method of Acyclovir

  Acyclovir is a synthetic purine nucleoside analogue. It is mainly used for various infections caused by herpes simplex virus. It can be used for initial or recurrent skin, mucous membrane, external genital infections and HSV infections in people with...

  • November 26, 2021
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  jessica Young wrote a new blog entry:

  Get to Know Immunoglobulins: IgA, IgM, IgG, IgE, IgD

  Many people can't read some of the symbols in the immunoglobulin test and have no idea what they mean or the significance and role of these tests. In fact, immunoglobulins are a class of proteins with antibody activity in human serum and body fluids. It h...

  • November 25, 2021
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  jessica Young wrote a new blog entry:

  Next-Generation Sequencing (NGS) Basics for Cancer Research

  Traditional diagnosis and therapies of cancer were heavily dependent on the histological classification of the tumor. With an emphasis on integrating molecular characteristics into diagnosis and the development of potential cancer therapies, increasi...

  • November 25, 2021
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  jessica Young wrote a new blog entry:

  What Are Probiotics and Can They Help Enhance Human Health?

  There are trillions of bacteria and other microorganisms in the human intestine, which together constitute the intestinal microflora. And the gut-associated lymphoid tissue (GALT) contains the vast majority and most complex pool of immune cells....

  • November 23, 2021
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  jessica Young wrote a new blog entry:

  Creative Biolabs Provides Custom γδ T Cells Products and Servic

  Since the discovery of Gamma delta T cells (γδ T cells), this rare and unique component of the immune system has been recognized for its potential in cancer immunology and immunotherapy. Creative Biolabs is a biotechnology company that has dev...

  • November 18, 2021
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  jessica Young wrote a new blog entry:

  The 12th ADC Drug Approved by the FDA

  Seagne and Genmab announced on September 20, 2021 that Tisotumab Vedotin has received accelerated approval from the FDA for the treatment of recurring or metastatic cervical cancer.
   
  Tivdak (Tisotumab vedotin-tftv) is an ADC produced by combining ...

  • November 18, 2021
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  jessica Young wrote a new blog entry:

  Cultivation of Anaerobic Bacteria Culture and Its Application

  Anaerobic bacterial culture is a method used to grow anaerobic bacteria from clinical specimens. Obligate anaerobes are bacteria that can only survive in the absence of oxygen. When exposed to the atmosphere for 10 minutes, obligate anaerobes are destroye...

  • November 17, 2021
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  jessica Young wrote a new blog entry:

  What Are Polymer Nanoparticles?

  Polymeric nanoparticles are particles within the size range from 1 to 1000 nm and can be loaded with active compounds entrapped within or surface-adsorbed onto the polymeric core. The term “nanoparticle” stands for both nanocapsules and nanosp...

  • November 16, 2021
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  jessica Young wrote a new blog entry:

  Profacgen Offers in Silico Protein-protein Interactions Predict

  Profacgen, a state-of-the-art protein service provider located in NY, USA, now utilizes advanced bioinformatics analysis platform and proven expertise to help customers meet their project needs. Supported by rich experience in the field, in silico PP...

  • November 15, 2021
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  jessica Young wrote a new blog entry:

  Advances in Research on Precise Biological Targeting Mechanisms

  Li Hongchang's research group at the Nanomedicine Technology Research Center of Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Yu Xuefeng's research group at the Material Interface Research Center and Li Yang's research group at t...

  • November 15, 2021
• 
  jessica Young wrote a new blog entry:

  m5C Profiling Services Now Available by CD Genomics’s RNA Solut

  RNA Solutions is the platform that offers services on the revolutionizing study of RNA, targeting both coding and non-coding RNAs of different physiological functions. The CD Genomics scientists are ready to help detect various types of RNA via meticulous...

  • November 15, 2021
• 
  jessica Young wrote a new blog entry:

  The biosynthetic process of steroid hormones

  Steroid drugs mainly include corticosteroids, sex hormones, progesterone and other types. They are endogenous substances found in the study of the endocrine system of mammals. They are used in maintaining life, mediating sexual function, body development,...

  • October 28, 2021
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  • October 28, 2021