Recent Entries

  • BOC Sciences Proudly Declares High PseudoUridine Productivity

    BOC Sciences, well known as the largest supplier of pseudoUridine in the world, announces that its yearly output currently surpasses 500 kg, indicating reliable efficiency and high productivity.   Along with the explosion of the COVID-19 pandemic, many vaccine companies have collabo...
  • Protein-Based Fluorescent Nanoparticles Available Now

    Fluorescent nanoparticles are those widely used for purposes of fluorescent imaging, mainly of cells and tissues. A strong fluorophore or fluorescent nanoparticles are internalized into cells so that they can be imaged. The only purpose of such fluorophores and nanomaterials is to render cells or ti...
  • What is the severity of the Omicron mutation?

    Recently, many scientists around the world summarized what they have learned about Omicron (an emerging variant of SARS-CoV-2) so far, as reported in Nature.   Researchers from all over the world are now studying the Omicron strain to learn more about its infectivity, pathogenicity, and immun...
  • Another PROTAC entered clinical study

    December 24, 2021—Accutar Biotechnology, a biotechnology company focused on AI drug development, announced that the FDA has approved its IND for AC0176 for the treatment of patients with metastatic decompensated refractory prostate cancer (mCRPC).   AC0176 is an orally administered chim...
  • Powering Pharma Future by Innovative Drug Delivery Solutions

    The history of drug administering can date back to the ancient Egyptian era, when sometimes clay pellets were used for drug delivery. Fast forward to the 1960s, when controlled drug delivery and time release systems were introduced, the technology at that time allowed for the slow/con...
  • Matched Antibody Pairs and Their Applications

    An antigen molecule could have multiple antigenic determinants, or known as epitopes. An antibody produced by the immune system can only bind to a specific epitope, while an antigen molecule could bind to different antibodies targeting different epitopes on the antigen. This unique feature has been ...
  • How to achieve target delivery of mRNA drugs to organs, cells,

    Cell Targeted Delivery In addition to organ-specific delivery, the researchers sought to target specific cell subpopulations in the liver by engineering ionizable lipid nanoparticles for selective delivery to hepatocytes and hepatic sinusoidal endothelial cells (LSECs). Increasing PEG content enhan...
  • Oncolytic Virus Engineering: The Future Key for Cancer Treatmen

    Oncolytic virus (OV) is a type of virus that can selectively infect and kill cancer cells. When infected cancer cells are destroyed by oncolysis, OVs continue to release new infectious virus particles to help destroy the remaining tumors without harming healthy tissue. Oncolytic viruses ca...
  • Creative Proteomics Announces the Launch of Its New Metabolomic

    Creative Proteomics is an integrated company that provides proteomics, metabolomics, glycomics, and bioinformatics analysis services to researchers in the pharmaceutical, biotechnology, agriculture and nutrition industries, as well as academic and government organizations. With the aim of developing...
  • Four Methods Helping the Study of Mitochondrial Gene Expression

    Harboring some circular and small genomes in human cells, mitochondria are recognizable for providing the cell with energy in the form of adenosine triphosphate (ATP) via OxPhos. However, with mitochondrial studies advancing, their significance was underestimated over the past. For example, oth...
  • CD Genomics: Targeted Proteomics Analysis Service Now Available

    Bioinformatics-analysis Platform belongs to CD Genomics, which provides reliable next-generation and third-generation high-throughput sequencing data analysis, comprehensive technology services, database construction, and other related data analysis business. The platform is a leading open solution ...
  • Fermentation process of vancomycin (II)

    Temperature and pH The growth and reproduction of bacteria and the synthesis of products are all based on the catalysis of enzymes, and the catalysis of enzymes is related to temperature and pH. Based on kinetic factors, how to control orderly becomes the key to research. In a certain range, th...
  • What Are Dextrans?

    Dextran is a polysaccharide comprised of d-glucopyranose (d-glucose) repeating units linked through glycosidic linkages. It is biocompatible, biodegradable, and presents antithrombotic and anti-inflammatory properties. Dextran functional hydroxyl (–OH) groups offer an easy point for ...
  • Creative BioMart Established a Novel Sub-brand Creative BioMart

    Creative BioMart, an internationally recognized leading supplier of recombinant proteins, recently established a novel sub-brand “Creative BioMart Recombinant Allergen” that focuses on allergen-related study.   Allergy is a common hypersensitivity disease in the world. It can be t...
  • Novel Protein Degradation Technologies: LYTACs and AbTACs

    TPD (targeted protein degradation) Proteins are the bearers of life activities, and their structure determines their function. Alterations in protein conformation frequently result in disease. The use of small molecules to selectively modulate protein function is fundamental to the treatment of...
  • Breakthrough! Scientists use rhesus monkey embryonic stem cells

    According to recent research, in the 1970s, the average male had 99 million sperm per milliliter of sperm, but by 2011, that number had plummeted to 47 million, a 53% decrease. According to Shanna Swan, an environmental medicine and public health professor at Mount Sinai's Icahn School of Medic...
  • Liposomes Usher in a New Era for Drug Delivery Research

    Recently, it is reported that some stunning breakthroughs have been made in gene-editing techniques to treat diversified diseases. Clustered regularly interspaced short palindromic repeat (CRISPR) is such a gene-editing achievement, which has attracted great attention because of its high e...
  • Nanopore direct sequencing of proteins with up to 100% accuracy

    Proteins are the primary constituents of living organisms and the primary carriers of life activities. Proteins with biological functions often have a certain spatial structure that is defined at various levels, the most important of which is the primary structure, i.e., the type ...
  • Bacterial Polysaccharides and Their Research Innovations

    Bacteria are covered by polysaccharides at the outer surface in the form of capsules, glycoproteins, or glycolipids. Such a bacterial sugar coat constitutes the principal antigens in most pathogenic bacteria and plays an important role in host-pathogen interactions. With mor...
  • The Wide Application of Escherichia coli Fermentation in Microb

    The microbial fermentation process has been manipulated by humans and is widely used in the production of various foods and other commercial products, including pharmaceuticals. Microbial fermentation can also be used to identify microorganisms for diagnostic purposes.    Several Gr...
  • Comprehensive protein interaction network helps discover candid

    Treatment options for COVID-19 remain limited. Researchers at the University of Helsinki and the University of Eastern Finland first searched for appropriate drug targets and reusable drugs and finally discovered six candidates with antiviral effects against SARS-CoV-2.   Understanding viral ...
  • Physicists have found new quantum effects in bilayer graphene

    Theorists at the University of Texas at Dallas and colleagues in Germany have for the first time observed a rare phenomenon in a very simple material, called the quantum anomalous Hall effect. Previous experiments have only found it in complex or subtle substances.   Fan Zhang, associate prof...
  • CD ComputaBio Announces 3D-QSAR Service for Drug Design and Scr

    CD ComputaBio, a reliable computational biology service provider located in New York, is always hammering at research and trials in order to provide customers with access to the latest software, technologies, and expertise at a competitive price and fast turnaround time. The company has recently lau...
  • APIs production through microbial fermentation

    There are many microorganisms in the world, and these microorganisms play a very important role in human life. At present, the most extensive application field of microorganisms is pharmaceuticals. With the help of the microbial fermentation, many drugs that are beneficial to human health can b...
  • What Are Chelating Agents?

    Chelating agents are organic compounds capable of linking together metal ions to form complex ring-like structures called chelates. They are also known as chelants, chelators, or sequestering agents. What Are Natural Chelating Agents? Citric, malic, lactic, and tartaric acids and certain&...