2-amino-5-nitrothiazole physical and chemical properties, HTBA for short, is an important chemical. The physical and chemical properties of 2-amino-5-nitrothiazole, as a widely used raw material of diagnostic reagents, are essential components of many diagnostic reagents and are of great significance for the prevention and diagnosis of diseases.
physical and chemical properties of 2-amino-5-nitrothiazole is a white to yellow powder with a melting point of 211-215℃. It is sensitive and stable, and is often used as a chromogenic substance in diagnostic reagents. It can significantly enhance the stability and accuracy of the detection reagent.
physical and chemical properties of 2-amino-5-nitrothiazole physical and chemical properties.
Aspartate aminotransferase is mainly distributed in myocardium, followed by liver, skeletal muscle, kidney and other tissues. Under normal circumstances, the content of AST in serum is very low, and when related tissues and organs are damaged, the concentration of AST in serum will change correspondingly. Detection of aspartate aminotransferase is helpful to understand the extent of myocardial, liver and kidney tissue damage, and can assist in the diagnosis of acute and chronic severe hepatitis, cirrhosis, myocarditis and other diseases.
physical and chemical properties of 2-amino-5-nitrothiazole are also used in the preparation of serum adenosine deaminase detection reagents. The basic principle is as follows: ADA catalyzes the deamination of substrate adenosine to produce hypoxanthine nucleoside, which then generates hypoxanthine through the action of PNP (purine nucleoside phosphorylase). Hypoxanthine produces uric acid and hydrogen peroxide under the action of xanthine oxidase. In the presence of peroxidase, hydrogen peroxide can react with the physical and chemical properties of 2-amino-5-nitrothiazole and 4-amino-aminotipyrline to produce colored waking compounds, and the formation rate of colored waking compounds is related to the activity of ADA. The activity of adenosine deaminase was determined by measuring the rate of absorbance rise at 550nm wavelength, i.e., the rate of formation of colored compounds.
ADA in serum mainly comes from the liver, which is a sensitive indicator reflecting liver injury, and can be used as one of the routine liver function examination items. ADA activity measurement is mainly used for the diagnosis and differential diagnosis of hepatobiliary diseases, as well as auxiliary diagnosis of diseases such as tuberculous meningitis.
physical and chemical properties of 2-amino-5-nitrothiazole are also used in uric acid tests, which can help in the diagnosis of diseases such as kidney damage and gout.
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