A greater emphasis cannot be placed on the importance of microscopic examination in the field of urine analysis than it already has been. However, while this is a straightforward method of obtaining useful information, it is also time-consuming and labor-intensive, and it necessitates the use of experienced personnel in order to ensure that the results and interpretations are of the highest possible accuracy and precision. An increasing number of automated urine analyzers have been developed and put into service in order to assist medical laboratories in the analysis of urine specimens. At the time of its inception, this study was intended to evaluate and compare the performance of three automated urine analyzers, which were the Cobas 6500, the UN3000-111b, and the iRICELL 3000. At the time of its introduction, the Cobas 6500, the UN3000-111b, and the iRICELL 3000 were the three most widely used automated urine analyzers on the market.
An important step forward has been made in recent years with the introduction of an entirely new generation of more sophisticated automated urinalysis machines into the marketplace. In the combination of fully automated microscopic and strip analyzer systems, it is possible to create fully automated workstations for a wide range of application requirements. Following this, three different systems were used to analyze the samples: an image-based analysis system (the iRICELL 3000 from Iris Diagnostics in Chatsworth, USA), a flow cytometry system (the UN 3000-111b from Sysmex Corporation in Kobe, Japan), and a Cobas 6500 from Roche in Mannheim, Germany. The researchers set out to compare the overall performance and effectiveness of these three automated urine analyzers, each of which used a different technology in conjunction with manual microscopy, as well as the performance of their chemical and microscopic examination components, in order to determine which was the most effective and efficient. They found that the performance of the automated urine analyzers was the most effective and efficient. We felt it was necessary to conduct the investigation in order to aid us in making a decision on which machine to purchase for our laboratory in order to aid us in making that decision.
Experiments carried out on urine samples are detailed in Section 2.1.
100 freshly collected urine specimens from admitted in- and out-patients who were submitted to the Microscopy Laboratory of the Department of Pathology at the Prince of Songkla University School of Medicine in Thailand for routine diagnostic urinalysis were selected and included in the study by using a random selection method. Three experienced medical technologists used a single microscope slide to collect samples from preservative-free containers and transfer them to four different test tubes for three different automated urine analyzers, all without the use of centrifugation or manual microscopy. Each sample was analyzed within two hours of being received at the laboratory, ensuring that all samples were analyzed as soon as possible.
An institutional ethics committee (REC.62-470-5-7) gave its approval for this study, which was carried out at the university's Faculty of Medicine, and the results were published as a result of the approval. In the case of a REC.62-470-5-7, this is an example of a REC.62-470-5-7.
Fully automated urine analyzers are those that are completely self-contained and operate entirely on autopilot.
2.2.1 The second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraph of the second paragraphThis is a formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalized formalIn many offices around the world, the Cobas 6500 (also known as the Cobas 6500) is a computer system manufactured by Cobas and used for various tasks.
Sysmex UN3000-111b (Sysmex UN3000-111b) Sysmex UN3000-111b (Sysmex UN3000-111b)Sysmex UN3000-111b (Sysmex UN3000-111b) Sysmex UN3000-111b (Sysmex UN3000-111b)Sysmex UN3000-111b (Sysmex UN3000-111b) Sysmex UN3000-111b (Sysmex UN3000-111b)Sysmex UN3000-111b (Sysmex UN3000-111b) Sysmex UN3000-111b (Sysmex UN3000-111b)
Integration of both the chemical component (UC-3500 analyzer) and the fluorescence flow cytometry component (UF-5000 analyzer) into a single platform is possible using a single instrument. Subsequently, the chemical component (UC-3500 analyzer) is examined under a microscope, and the fluorescence flow cytometry component (UF-5000 analyzer) is examined under a microscope. By employing the reflectance photometry technique, which is employed by the UC-3500 analyzer, it is possible to determine the levels of leukocytes, erythrocytes, nitrite, protein, glucose, ketones, uribilinogen, and bilirubin in a sample as well as the pH, color, and turbidity of the sample in a sample. As well as determining the pH of a sample, it can also be used to determine the color and clarity of a sample, among other things. In addition to determining the specific gravity of a sample, this technique can be used to determine the specific gravity of other samples, as well as their other properties. It is possible to perform forward scatter and fluorescence detection, as well as adaptive cluster analysis and adaptive clustering, with the UF-5000 analyzer. Additionally, the UN3000-111b contains the UD-10, which is a urine particle digital imaging device that, among other things, captures images of urine and categorizes the particles into eight sizes classes based on their size, among other features. The UD-10 also provides the user with a close-up view of urine particles, which is particularly useful. Immediately following the completion of the particle analysis, the UD-10 device confirms that the results are abnormal, indicating that the procedure was completed successfully.
The iRICELL 3000 is comprised of two components: a chemical analyzer (the iChemVELOCITY) and a microscopic examination component (the iQ200). The iChemVELOCITY is the chemical analyzer component. It is through the collaboration of these two components that a comprehensive solution for the analysis of biological specimens can be provided. It uses Digital Flow Morphology technology in conjunction with Auto-Particle Recognition (APR) software to identify, classify, and quantify the cells and particles present in uncentrifuged urine. The Iris iQ200 analyzes urine to identify, classify, and quantify the cells and particles present. It is possible to see the results on a computer screen. According to the researchers, APR software is used to identify and count the hundreds of images captured by the flow cell's digital camera after a urine specimen is image captured in a planar plane by hydrodynamic focusing sheath fluid and then transferred to a computer for analysis. Each particle is then automatically classified based on its size, shape, contrast, and texture, among other characteristics. The results are divided into 12 particle categories: red blood cells (RBCs), white blood cells (WBCs), WBC clumps, hyaline casts, pathological casts (or unclassified casts), squamous epithelial cells, non-squamous epithelial cells, bacteria, yeasts, crystals, mucus, and sperm. The results are divided into 12 particle categories: red blood cells (RBCs), white blood cells (The results have been divided into 12 particle categories, which are as follows:Red blood cells (RBCs) and white blood cells (WBCs) are two types of blood cells.) There are 12 different types of blood cells identified in the results: red blood cells (RBCs), white blood cells (RBCs), white blood cells (WBCs), and white blood cell clumps are all examples of the types of blood cells identified.